129422-86-2Relevant academic research and scientific papers
Peptide-catalyzed regio- and enantioselective reduction of α,β,γ,δ-unsaturated aldehydes
Akagawa, Kengo,Sen, Jun,Kudo, Kazuaki
, p. 11585 - 11588 (2013)
A resin-supported peptide catalyst (see box in the scheme) was used in the title reaction. The inherent regioselectivity was overcome by the peptide catalyst to promote the 1,6-selective reaction prior to 1,4-reduction. High stereoconvergence was also achieved when using a mixture of geometric isomers of the starting aldehydes. Ach=1-amino-1-cyclohexanecarboxylic acid. Copyright
