129432-25-3Relevant articles and documents
Synthesis of nevirapine and its major metabolite
Grozinger,Fuchs,Hargrave,Mauldin,Vitous,Campbell,Adams
, p. 259 - 263 (1995)
Several synthetic methods were developed during the process optimization for the large scale synthesis of nevirapine (1), a non-nucleoside inhibitor of HIV-1 Reverse Transcriptase. The synthesis of its putative major metabolite 11-cyclopropyl-5,11-dihydro-4-hydroxymethyl-6H-[3,2-b:2',3'-e][1,4]dia zepin-6-one (2) and the oxidation of 2 to the corresponding aldehyde 3, are described.
COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE
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, (2019/01/06)
The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
Method for the preparation of 5,11-dihydro-6h-dipyrido [3,2-b:2',3'-e][1,4]diazepines
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, (2008/06/13)
This invention relates to a novel method for preparing certain dipyrido-diazepines.