1294449-05-0

Basic information

• Product Name: C₂₁H₃₁ClF₃O₆P
• CAS NO: 1294449-05-0
• Molecular Weight: 502.896
• Mol File: 1294449-05-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₃₁ClF₃O₆P(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₃₁ClF₃O₆P(1294449-05-0)
• EPA Substance Registry System: C₂₁H₃₁ClF₃O₆P(1294449-05-0)

Safety Data

• Hazardous Substances Data: 1294449-05-0(Hazardous Substances Data)

Upstream product

• 14273-86-0 methyl 5-chloropentanoate 
• 20074-80-0 5-chloro-pentanal 
• 39637-99-5 (S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride 
• 1294448-86-4 diisopropyl [5-chloro-1-(chloroacetoxy)pentyl]phosphonate 
• 1294448-82-0 diisopropyl (5-chloro-1-hydroxypentyl)phosphonate 

Relevant articles and documents

Chemoenzymatic synthesis of phosphonic acid analogues of L-lysine, L-proline, L-ornithine, and L-pipecolic acid of 99 % ee - Assignment of absolute configuration to (-)-proline

(±)-ω-Halo-α-(chloroacetoxy)phosphonates were kinetically resolved by use of a protease (Chirazyme P-2). The esters recovered at levels of conversion between 56 and 72 % furnished (S)-alcohols of 99 % ee. These were converted via azides into the phosphonic acid analogues of L-lysine, L-proline, L-ornithine and L-pipecolic acid. (-)-Phosphaproline was transformed into crystalline ureas derived from (R)- and (S)-1-phenylethyl isocyanate. X-ray structure analyses revealed that the levorotary phosphaproline has the R configuration, contrary to earlier reports. Copyright