1294512-63-2Relevant academic research and scientific papers
A new synthesis of fully phosphorylated flavones as potent pancreatic cholesterol esterase inhibitors
Peng, Guoping,Du, Yidan,Wei, Yingling,Tang, Jingming,Peng, Ai-Yun,Rao, Liqun
, p. 2530 - 2534 (2011)
Five flavones possessing one to four phenolic groups were fully phosphorylated efficiently and the obtained compounds showed excellent pancreatic cholesterol esterase (CEase) inhibitory activities with IC 50 in the nanomolar range, which were m
Synthesis and biological evaluation of phosphorylated flavonoids as potent and selective inhibitors of cholesterol esterase
Wei, Yingling,Peng, Ai-Yun,Wang, Bo,Ma, Lin,Peng, Guoping,Du, Yidan,Tang, Jingming
, p. 751 - 758 (2014/03/21)
A series of phosphorylated flavonoids were synthesized and investigated in vitro as inhibitors of pancreatic cholesterol esterase (CEase) and acetylcholinesterase (AChE). The results showed that most of the synthesized compounds exhibited nanomolar potenc
