129488-38-6Relevant academic research and scientific papers
Metal-free synthesis of alkynyl imines using an oxophosphonium-mediated approach at ambient temperatures
Dong, Qing-Li,Liu, Guan-Sai,Zhou, Hai-Bin,Chen, Lin,Yao, Zhu-Jun
, p. 1636 - 1640 (2008/09/18)
A metal-free approach was developed for the mild synthesis of N-aryl α-alkynyl imines from corresponding amide precursors for the first time. The electronic effects of substrates and the reaction mechanisms were investigated and discussed. This newly deve
Discovery of novel triazole-based opioid receptor antagonists
Zhang, Qiang,Keenan, Susan M.,Peng, Youyi,Nair, Anil C.,Yu, Seong Jae,Howells, Richard D.,Welsh, William J.
, p. 4044 - 4047 (2007/10/03)
We report the computer-aided design, chemical synthesis, and biological evaluation of a novel family of δ opioid receptor (DOR) antagonists containing a 1,2,4-triazole core structure that are structurally distinct from other known opioid receptor active l
Pharmaceutical compositions containing phenylamides
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, (2008/06/13)
Pharmaceutical compositions for inhibiting the aggregation of erthyrocytes or thrombocytes which include phenylamides which conform to the formula: STR1 with R1-6, X, A and B being as defined. Processes for the preparation of novel phenylamides
