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Boc-Tyr(But)-D-Ala-Phe-Gly-ψ(NHCO)-Tyr-Pro-OBut is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

129505-65-3

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129505-65-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 129505-65-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,5,0 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 129505-65:
(8*1)+(7*2)+(6*9)+(5*5)+(4*0)+(3*5)+(2*6)+(1*5)=133
133 % 10 = 3
So 129505-65-3 is a valid CAS Registry Number.

129505-65-3Relevant academic research and scientific papers

Opioid peptides. Synthesis and biological properties of demorphin related hexapeptides

Salvadori,Marastoni,Balboni,Borea,Tomatis

, p. 171 - 177 (2007/10/02)

The Gly4 and/or Tyr5 residues in dermorphin hexapeptide (H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-OH) were replaced by Nα-methyl- or D-amino acids in order to examine the effect on opioid activity. Two pseudopeptides (H-Tyr-D-Ala-Phe-Gly-ψ (NHCO)-Xaa-Pro-OH, Xaa - Tyr or Phe) in which the Gly4-Xaa bond is reversed, were also prepared. Metabolic stability, analgesia and selectivity of these compounds for different receptor populations have been investigated. Results suggest that the 12 new analogues showed a negligible affinity for the K binding site and some selectivity for μ- or δ receptors. In some cases the analgesic potencies seems to be related to enzymatic stability of the peptides.

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