129535-80-4Relevant articles and documents
Inhibitors of squalene synthetase and protein farnesyltransferase
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, (2008/06/13)
The present invention provides a compound of the formula STR1 which inhibit squalene synthetase and cholesterol biosynthesis and are useful in the treatment of e.g., hyperlipidaemia, atherosclerosis, or fungal infections, processes for the preparation of the compounds of the invention, intermediates useful in these processes, and pharmaceutical compositions containing the compounds.