129544-55-4

Upstream product

• 783-08-4 [4-(benzylideneamino)phenyl]methanol 
• 129544-46-3 3-Dimethylaminomethyl-1-(4-methoxy-phenyl)-4-phenyl-azetidin-2-one 

Downstream Products

• 60561-74-2 N-(p-methoxy)phenyl phenylglycine 
• 94612-33-6 1-(4-methoxyphenyl)-4-phenylazetidine-2,3-dione 

Relevant academic research and scientific papers

Preparation of α-Methylene and α-Ethylidene β-Lactams via the Ester Enolate-Imine Condensation Using β-(Dialkylamino) Esters as Starting Materials: Scope and Synthetic Applications

A new, simple procedure for the preparation of appropriately substituted α-methylene and α-ethylidene β-lactams via the ester enolate-imine condensation is described.The method is based on the use of lithium 3-(dialkylamino) ester enolates as synthetic eq

A novel synthetic approach to α-alkylidene-β-lactams

A simple strategy for the synthesis of various α-alkylidene-β-lactams 4 based upon the condensation between lithium enolates of 3-(N,N-dialkylamino)esters and imines followed by straightforward deamination of the resulting 3-aminoalkyl-β-lactams 3 is outlined. The synthesis of α-alkylidene-β-formyl-β-lactams is a particularly significant feature of this work.