1295568-49-8Relevant articles and documents
Kilogram synthesis of (S)-3-aminopyran from l -glutamic acid
Savage, Scott,Babu, Srinivasan,Zak, Mark,Mao, Zhongping,Cao, Jianhua,Ge, Yonghui,Ma, Dongxu,Jiang, Guoqiang
, p. 987 - 990 (2013)
We describe the development of a concise route to prepare kilogram quantities of (S)-3-aminopyran, a key intermediate in the synthesis of a Jak1 inhibitor. The chiral amine was introduced via a chiral-pool approach and involves using inexpensive, commerci