1295646-18-2Relevant academic research and scientific papers
Enzymatic approach to cascade synthesis of bis(indolyl)methanes in pure water
Fang, Ke,Fu, Yajie,He, Xinyi,Hu, Yi,Lu, Zeping,Xu, Huajin
, p. 10848 - 10853 (2020/03/27)
A mild, efficient, and green protocol was developed for the synthesis of bis(indolyl)methanes catalyzed by lipase TLIM through the cascade reactions of indole with aldehydes in pure water. This methodology offers many superiorities such as excellent yields, wide substrate range, simple procedure, reusable and minimal amount of catalyst, and the ability to be scaled up.
Ionic liquid tributyl (carboxymethyl) phosphonium bromide as an efficient catalyst for the synthesis of bis(indolyl)methanes under solvent-free conditions
Khazaei, Ardeshir,Zolfigol, Mohammad Ali,Faal-Rastegar, Toktam
, p. 617 - 619 (2013/11/06)
A simple green synthesis of bis (indolyl)methanes involved the reaction of indole with aldehydes in the presence of a phosphonium salt ionic liquid as the catalyst. The simple experimental procedures, short reaction times, high yields of product, non-toxi
Room-temperature synthesis of diindolylmethanes using silica-supported sulfuric acid as a reusable catalyst under solvent-free conditions
Zhang, Yan,Chen, Xiang,Liang, Jun,Shang, Zhi-Cai
experimental part, p. 2446 - 2454 (2011/08/07)
Efficient electrophilic substitution reactions of indoles with various aromatic and aliphatic aldehydes were carried out using a catalytic amount of H2SO4SiO2 under solvent-free conditions to afford the corresponding bis(indolyl)methanes in excellent yields.
Niobium(V) pentachloride-catalyzed efficient and highly rapid synthesis of bis(indolyl)-methanes under mild conditions
Kidwai, Mazaahir,Bura, Nisha,Mishra, Neeraj Kumar
experimental part, p. 229 - 232 (2011/03/23)
Niobium(V) pentachloride has been found to be an extremely efficient catalyst for electrophilic substitution reaction of indole using various aromatic aldehydes at room temperature, to afford the corresponding bis(indolyl)methanes in good yields. The rema
