1295722-66-5Relevant academic research and scientific papers
Kilogram synthesis of (S)-3-aminopyran from l -glutamic acid
Savage, Scott,Babu, Srinivasan,Zak, Mark,Mao, Zhongping,Cao, Jianhua,Ge, Yonghui,Ma, Dongxu,Jiang, Guoqiang
, p. 987 - 990 (2013/07/05)
We describe the development of a concise route to prepare kilogram quantities of (S)-3-aminopyran, a key intermediate in the synthesis of a Jak1 inhibitor. The chiral amine was introduced via a chiral-pool approach and involves using inexpensive, commerci
TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF AS JAK INHIBITORS
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Page/Page column 110, (2013/03/26)
The invention provides novel compounds of formula I having the general formula:(I) wherein Rl s R2, R3, X and Y are as described herein. Accordingly, the compounds may be provided in pharmaceutically acceptable compositions and used for the treatment of immunological or hyperproliferative disorders.
