129578-09-2

Basic information

• Product Name: diacetylgoniofufurone
• CAS NO: 129578-09-2
• Molecular Weight: 334.326
• Mol File: 129578-09-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diacetylgoniofufurone(CAS DataBase Reference)
• NIST Chemistry Reference: diacetylgoniofufurone(129578-09-2)
• EPA Substance Registry System: diacetylgoniofufurone(129578-09-2)

Safety Data

• Hazardous Substances Data: 129578-09-2(Hazardous Substances Data)

Upstream product

• 129578-06-9 (+/-)-goniofufurone 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Novel Bioactive Styryl-lactones: Goniofufurone, Goniopypyrone, and 8-Acetylgoniotriol from Goniothalamus giganteus (Annonaceae). X-Ray Molecular Structure of Goniofufurone and of Goniopypyrone

By use of brine shrimp lethality for activity-directed fractionation, three novel styryl-lactones which are cytotoxic to human tumor cells, goniofufurone, goniopypyrone, and 8-acetylgoniotriol, have been isolated from ethanolic extracts of the stem bark of Goniothalamus giganteus Hook. f., Thomas (Annonaceae).The structures were elucidated by IR, mass, 1H NMR, 13C NMR, and 2D NMR (1H-1H COSY), and 1H-13C HETCOR) spectra.The structures of goniofufurone and goniopypyrone, which represent unusual natural skeletons, were confirmed by X-ray cristallographic analysis, to help establish the relative configurations.Goniopypyrone was the most bioactive, showing nonselective ED50 values of ca. 6.7*10-1 μg/ml in each of our three human tumor cell lines.