129611-32-1

Basic information

• Product Name: 2-Bromo-3-hydroxy-6-iodopyridine
• Synonyms: 2-Bromo-3-hydroxy-6-iodopyridine;2-Bromo-6-iodo-3-pyridinol;2-broMo-6-iodopyridin-3-ol
• CAS NO: 129611-32-1
• Molecular Formula: C₅H₃BrINO
• Molecular Weight: 299.9
• EINECS: 215-596-9
• Product Categories: alcohol| alkyl bromide| alkyl Iodine
• Mol File: 129611-32-1.mol
• Article Data: 32

Chemical Properties

• Melting Point: 141-142 °C(Solv: chloroform (67-66-3))
• Boiling Point: 403.961 °C at 760 mmHg
• Flash Point: 198.109 °C
• Appearance: /
• Density: 2.513 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 3.96±0.10(Predicted)
• CAS DataBase Reference: 2-Bromo-3-hydroxy-6-iodopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-3-hydroxy-6-iodopyridine(129611-32-1)
• EPA Substance Registry System: 2-Bromo-3-hydroxy-6-iodopyridine(129611-32-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 129611-32-1(Hazardous Substances Data)

Usage

General Description

2-Bromo-3-hydroxy-6-iodopyridine is a chemical compound that belongs to the pyridine family. It is a yellow crystalline solid with the molecular formula C5H3BrINO. 2-Bromo-3-hydroxy-6-iodopyridine is used in the synthesis of pharmaceuticals and agricultural chemicals. It has potential applications in the development of new drugs due to its biological activity and ability to interact with various biological targets. Additionally, it is used as an intermediate in organic synthesis and is an important building block for the preparation of more complex molecules. This chemical's unique structure and properties make it a valuable tool in the field of medicinal and chemical research.

Upstream product

• 6602-32-0 2-bromo-pyridin-3-ol 

Downstream Products

• 1609573-52-5 2,6-bis(4-chlorophenyl)pyridin-3-ol 
• 1609655-11-9 2-bromo-6-(4-chlorophenyl)pyridin-3-ol 
• 1581767-47-6 2-ethoxy-3-methoxy-5-bromo-6-(4-fluorophenyl)pyridine 
• 1581767-03-4 5-bromo-6-(4-fluorophenyl)-3-hydroxypyridin-2(1H)-one 
• 1581766-97-3 6-(3,4-dihydroxyphenyl)-3-hydroxypyridin-2(1H)-one 
• 1452670-56-2 4,4,5,5-tetramethyl-2-(5-(2-bromo-3-(trifluoromethanesulfonyloxy)pyridine-6-yl)thiophen-2-yl)-1,3,2-dioxaborolane 
• 1402798-87-1 (4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-3-((2-(6-isopropyl-3-methoxypyridin-2-yl)-5,5-dimethylcyclohex-1-enyl)methyl)-4-methyloxazolidin-2-one 
• 1423047-55-5 C₃₀H₃₄F₆N₂O₄ 

Relevant articles and documents

Halogenation of pyridinols using bis(sym-collidine)iodine(I) and bis(sym-collidine)bromine(I) hexafluorophosphate

Iodination and bromination of pyridinols was achieved by action of the title reagents in methylene chloride.

Boron Containing PDE4 Inhibitors

The present invention relates to boron containing compounds of Formula (I) [in-line-formulae]X—Y—Z?? Formula (I)[/in-line-formulae] that inhibit phosphodiesterase 4 (PDE4). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating diseases, conditions, or disorders ameliorated by inhibition of PDE4.

Fused tricyclic compound and application in medicines

The invention relates to a condensed tricyclic compound and application in medicines, particularly to application of the condensed tricyclic compound as a medicine for treating and/or preventing hepatitis B. Specifically the present invention relates to a