129611-92-3

Basic information

• Product Name: (2E,4E)-7,7-Bis-methylsulfanyl-1-phenyl-hepta-2,4,6-trien-1-ol
• CAS NO: 129611-92-3
• Molecular Weight: 278.439
• Mol File: 129611-92-3.mol

Chemical Properties

• CAS DataBase Reference: (2E,4E)-7,7-Bis-methylsulfanyl-1-phenyl-hepta-2,4,6-trien-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2E,4E)-7,7-Bis-methylsulfanyl-1-phenyl-hepta-2,4,6-trien-1-ol(129611-92-3)
• EPA Substance Registry System: (2E,4E)-7,7-Bis-methylsulfanyl-1-phenyl-hepta-2,4,6-trien-1-ol(129611-92-3)

Safety Data

• Hazardous Substances Data: 129611-92-3(Hazardous Substances Data)

Upstream product

• 129611-80-9 5,5-bis(methylthio)-2,4-pentadienal 
• 15081-72-8 4,4-bis-methylsulfanyl-but-3-en-2-ol 
• 17649-86-4 4,4-bis(methylthio)but-3-en-2-one 
• 129611-85-4 7,7-bis(methylthio)-1-phenyl-2,4,6-heptatriene-1-one 
• 129611-82-1 7,7-bis(methylthio)-2,4,6-heptatrienal 

Downstream Products

• 56495-90-0 methyl (2E,4E,6E)-7-phenylhepta-2,4,6-trienoate 

Relevant articles and documents

A new 1,5- to 1,11-carbonyl transposition protocol involving ketene dithioacetal chemistry: An efficient polyene synthesis

An efficient strategy for alternative 1,5-, 1,7-, 1,9- and 1,11- carbonyl transposition has been developed via 1,2-reductive or alkylative addition to 5,5-bis(methylthio)-2,4-pentadienals 3a-b, 7,7-bis(methylthio)-2,4,6-heptatrienones 5,9,9-bis(methylthio)-2,4,6,8-nonatetraenones 8 and 11,11-bis(methylthio)-2,4,6,8,10-undecapentaenones 11 followed by BF3,Et2O induced methanolysis of the resulting carbinols to the corresponding polyene esters. The synthesis of the novel polyene aldehydes 3a-b, 7a-b, 10b and polyenones 5, 8, 11 precursors has also been described following iterative Vielsmeier-Haack reaction and aldol condensation.

OXOKETENE DITHIOACETALS AS VERSATILE SYNTHONS FOR ALTERNATIVE 1,3 TO 1,11 CARBONYL TRANSPOSITIONS: A NEW POLYENE SYNTHESIS

A model strategy for 1,7 to 1,11 carbonyl transpositions involving 1,2 addition of sodium borohydride or Grignard reagents to polyenyl oxoketene dithioacetals 8 obtained by condensation of bis(methylthio)polyenals 1-3 with active methylene ketones, followed by borontrifluoride etherate catalyzed methanolysis of the resulting polyenyl carbinol acetals 9 to give 1,n transposed polyene esters 10 has been described.