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(E)-3-(2-aminophenyl)-N-(4-(1-benzoylpiperidin-4-yl)butyl)acrylamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1296137-08-0 Structure
  • Basic information

    1. Product Name: (E)-3-(2-aminophenyl)-N-(4-(1-benzoylpiperidin-4-yl)butyl)acrylamide
    2. Synonyms: (E)-3-(2-aminophenyl)-N-(4-(1-benzoylpiperidin-4-yl)butyl)acrylamide
    3. CAS NO:1296137-08-0
    4. Molecular Formula:
    5. Molecular Weight: 405.54
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1296137-08-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (E)-3-(2-aminophenyl)-N-(4-(1-benzoylpiperidin-4-yl)butyl)acrylamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: (E)-3-(2-aminophenyl)-N-(4-(1-benzoylpiperidin-4-yl)butyl)acrylamide(1296137-08-0)
    11. EPA Substance Registry System: (E)-3-(2-aminophenyl)-N-(4-(1-benzoylpiperidin-4-yl)butyl)acrylamide(1296137-08-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1296137-08-0(Hazardous Substances Data)

1296137-08-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1296137-08-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,9,6,1,3 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1296137-08:
(9*1)+(8*2)+(7*9)+(6*6)+(5*1)+(4*3)+(3*7)+(2*0)+(1*8)=170
170 % 10 = 0
So 1296137-08-0 is a valid CAS Registry Number.

1296137-08-0Downstream Products

1296137-08-0Relevant articles and documents

Design, synthesis and X-ray crystallographic study of NAmPRTase inhibitors as anti-cancer agents

You, Hyun,Youn, Hyung-Seop,Im, Isak,Bae, Man-Ho,Lee, Sang-Kook,Ko, Hyojin,Eom, Soo Hyun,Kim, Yong-Chul

, p. 1153 - 1164 (2011/04/17)

NAmPRTase (PBEF/Visfatin) plays a pivotal role in the salvage pathway of NAD+ biosynthesis. NAmPRTase has been an attractive target for anti-cancer agents that induce apoptosis of tumor cells via a declining plasma NAD+ level. In this report, a series of structural analogs of FK866 (1), a known NAmPRTase inhibitor, was synthesized and tested for inhibitory activities against the proliferation of cancer cells and human NAmPRTase. Among them, compound 7 showed similar anti-cancer and enzyme inhibitory activities to compound 1. Further investigation of compound 7 with X-ray analysis revealed a co-crystal structure in complex with human NAmPRTase, suggesting that Asp219 in the active site of the enzyme could contribute to an additional interaction with the pyrrole nitrogen of compound 7.

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