129619-37-0Relevant articles and documents
One-Pot Absolute Stereochemical Identification of Alcohols via Guanidinium Sulfate Crystallization
Brummel, Beau R.,Lee, Kinsey G.,McMillen, Colin D.,Kolis, Joseph W.,Whitehead, Daniel C.
, p. 9622 - 9627 (2019/12/02)
A novel technique for the absolute stereochemical determination of alcohols has been developed that uses crystallization of guanidinium salts of organosulfates. The simple one-pot, two-step process leverages facile formation of guandinium organosulfate single crystals for the straightforward determination of the absolute stereochemistry of enantiopure alcohols by means of X-ray crystallography. The strong hydrogen bonding network drives the stability of the crystal lattice and allows for a diverse range of organic alcohol substrates to be analyzed.
Stereoselective reduction of unsaturated 1,4-diketones. A practical route to chiral 1,4-diols
Bach, Jordi,Berenguer, Ramon,Garcia, Jordi,Loscertales, Teresa,Manzanal, Judith,Vilarrasa, Jaume
, p. 1091 - 1094 (2007/10/03)
A new synthetic route to C2-symmetric chiral 1,4-diols based on the borane-mediated oxazaborolidine-catalysed reduction of 2-ene-1,4-diones (2), of 2-yne-1,4-diones (3), and/or of Co-complexed diketones 4 is described. Good to excellent enantio- and diastereoselectivities have been obtained in the reduction of diketones 3 and 4, catalysed by oxazaborolidines 6 and 5, respectively.
