129647-10-5

Basic information

• Product Name: (2R,5R)-2,5-dimethyl-1-phenylphospholane
• Synonyms: (2R,5R)-2,5-dimethyl-1-phenylphospholane
• CAS NO: 129647-10-5
• Molecular Weight: 192.241
• Mol File: 129647-10-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (2R,5R)-2,5-dimethyl-1-phenylphospholane(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,5R)-2,5-dimethyl-1-phenylphospholane(129647-10-5)
• EPA Substance Registry System: (2R,5R)-2,5-dimethyl-1-phenylphospholane(129647-10-5)

Safety Data

• Hazardous Substances Data: 129647-10-5(Hazardous Substances Data)

Usage

General Description

(2R,5R)-2,5-dimethyl-1-phenylphospholane is a chemical compound with the molecular formula C11H15P. It is a phospholane, which is a type of heterocyclic compound containing a phosphorus atom in a five-membered ring. This particular compound features a phenyl group attached to a phosphorus atom and two methyl groups attached to the carbon atoms in the ring. It is often used as a ligand in organometallic chemistry and catalysis, where it can coordinate to metal atoms and influence their reactivity. The stereochemistry of the compound, with the 2R,5R configuration, is important for its behavior as a ligand and its interactions with other molecules. Overall, (2R,5R)-2,5-dimethyl-1-phenylphospholane is a versatile compound with potential applications in various chemical processes.

Upstream product

• 119008-52-5 (S,S)-2,5-bis(methylsulfonyloxy)hexane 
• 638-21-1 phenylphosphane 
• 220224-82-8 (4S,7S)-4,7-dimethyl-1,3,2-dioxathiepane 2,2-dioxide 
• 13595-56-7 dilithium phenylphosphide 
• 644-97-3 Dichlorophenylphosphine 
• 34338-96-0 (2S,5S)-2,5-hexanediol 
• 110-13-4 2,5-hexanedione 
• 108-86-1 bromobenzene 
• 1754-49-0 diethyl phenylphosphonate 

Downstream Products

• 768-32-1 trimethylphenylsilane 
• 505092-85-3 (2R,5R)-2,5-dimethyl-1-(trimethylsilyl)phospholane 
• 1363406-55-6 bis((2R,5R)-2,5-dimethylphospholanomethyl)(diphenylmethyl)amine 
• 1363406-54-5 (benzyl)bis((2R,5R)-2,5-dimethylphospholanomethyl)amine 

Relevant articles and documents

Olefination of ketenes for the enantioselective synthesis of allenes via an ylide route

Pseudo-C2-symmetric chiral phosphorus ylide is designed and synthesized for the enantioselective preparation of allenic esters, amides, ketone, and nitrile. Up to 92% ee is achieved.

Synergistic effects of hemilabile coordination and counterions in homogeneous catalysis: New tunable monophosphine ligands for hydrovinylation reactions [15]

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New chiral phospholanes; synthesis, characterization, and use in asymmetric hydrogenation reactions

We describe the practical synthesis of enantiomerically pure trans-2,5-disubstituted-1-phenylphospholanes which are then employed in the preparation of a new series of C2-symmetric bis- and C3-symmetric tris(phospholane) ligands. A versatile three-step route to the important chiral 1,4-diol intermediates, used in the phosphine syntheses, is outlined. Rhodium complexes bearing the new phosphine ligands were prepared and shown to act as efficient catalyst precursors for the enantioselective hydrogenation of various unsaturated substrates.