1296868-84-2Relevant academic research and scientific papers
Palladium-catalyzed C-H perfluoroalkylation of arenes
Loy, Rebecca N.,Sanford, Melanie S.
supporting information; experimental part, p. 2548 - 2551 (2011/06/22)
A new Pd-catalyzed reaction for the coupling between perfluoroalkyl iodides (RFI) and simple aromatic substrates is described. The perfluoroalkylated arene products are obtained in good to excellent yields in the presence of a phosphine-ligated Pd catalyst and Cs2CO3 as a base. The development, optimization, scope, and preliminary mechanistic studies of these transformations are reported.
