129687-62-3Relevant academic research and scientific papers
(3R,5S,7as)-(3,5-bis(4-fluorophenyl)tetrahydro-1h-oxazolo[3,4-c] oxazol-7a-yl)methanol, a novel neuroprotective agent
Desino, Kelly E.,Ansar, Sabah,Georg, Gunda I.,Himes, Richard H.,Michaelis, Mary Lou,Powell, Douglas R.,Reiff, Emily A.,Telikepalli, Hanumaiah,Audus, Kenneth L.
, p. 7537 - 7543 (2009)
Compounds that interact with microtubules, such as paclitaxel, have been shown to possess protective properties against β-amyloid (Aβ) induced neurodegeneration associated with Alzheimer's disease. In this work, the novel agent (3R,5S,7as)-(3,5-bis(4-fluo
Neuroprotective agents
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Page/Page column 7, (2008/06/13)
Novel stereoisomers of GS-164 are provided. The compounds, such as (3R,5S,7as)-(3,5-bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a-yl)methanol (TH-237A) and (3R,5S,7as)-(3,5-bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a-yl)methanol (T
Genotoxicity in oxazolidine derivatives: influence of the nitro group
Vanelle, P,Meo, MP De,Maldonado, J,Nouguier, R,Crozet, MP,et al.
, p. 241 - 250 (2007/10/02)
Tris-(hydroxymethyl)-aminomethane reacts with various aromatic or heterocyclic aldehydes, leading to new mono- or bicyclic oxazolidine derivatives.The importance of molecular surroundings of the nitro group has been evaluated by the genotoxic study of syn
