129767-30-2Relevant academic research and scientific papers
Muscarinic receptor antagonists
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, (2008/06/13)
Compounds of the formula STR1 and the pharmaceutically acceptable salts thereof, wherein: Y is a direct link, --CH 2 --, --(CH 2) 2 --, --CH 2 O-- or --CH 2 S--; R is --CN or --CONH 2 ; and R 1 is STR2 where X and X 1 are each independently O or CH 2 ; and m is 1, 2 or 3, are muscarinic receptor antagonists useful in the treatment of diseases and conditions associated with the altered motility and/or tone of smooth muscle, such as irritable bowel syndrome.
