129768-48-5 Usage
General Description
2-[(2-CHLOROPROPANOYL)AMINO]BENZAMIDE, also known as Cysteaminyl Hydrochloride, is a chemical compound with the molecular formula C10H12ClN3O2. It is a derivative of benzamide and contains a chloropropionylamine group. 2-[(2-CHLOROPROPANOYL)AMINO]BENZAMIDE is known for its potential as an anticancer agent, with research suggesting that it may have anti-proliferative and cytotoxic effects on cancer cells. It has also been studied for its potential role in modulating cellular processes and as a potential therapeutic agent for various diseases. Additionally, 2-[(2-CHLOROPROPANOYL)AMINO]BENZAMIDE has been investigated for its potential as a treatment for osteoporosis and as an inhibitor of the enzyme transglutaminase, which is involved in the progression of neurodegenerative diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 129768-48-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,7,6 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 129768-48:
(8*1)+(7*2)+(6*9)+(5*7)+(4*6)+(3*8)+(2*4)+(1*8)=175
175 % 10 = 5
So 129768-48-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H11ClN2O2/c1-6(11)10(15)13-8-5-3-2-4-7(8)9(12)14/h2-6H,1H3,(H2,12,14)(H,13,15)
129768-48-5Relevant articles and documents
Synthesis of chrysogine, a metabolite of Penicillium chrysogenum and some related 2-substituted 4-(3H)-quinazolinones
Bergman, Jan,Brynolf, Anna
, p. 1295 - 1310 (2007/10/02)
Syntheses of both enantiomers of chrysogine, 2-(α-hydroxyethyl)-4(3H)-quinazolinone, 1 from 2-ammobenzamide are reported. Thus reaction of 2-aminobenzamide and optically active α-acetoxypropionyl chloride gave 9, which upon saponification and cyclization induced by aqueous sodium carbonate at room temperature gave chrysogine. The enantiomeric purity of 1 was determined by NMR. Inversion of (-)-(S)-1, using the Mitsunobo reaction, gave (+)-(R)-1. Reduction of 2-acetyl-4(3H)-qumazolinone 2 with baker's yeast gave the S-enantiomer of 1. The cyclization method used could be extended and a number of 2-(a-hydroxy)alkyl-4-(3H)-quinazolinones are also reported.
