129768-69-0 Usage
Uses
Used in Pharmaceutical Industry:
2-Quinazolinecarboxylic acid, 1,2,3,4-tetrahydro-2-methyl-4-oxo-, is used as a key intermediate in the synthesis of various pharmaceutical compounds for [application reason]. Its unique structure allows for the development of drugs with novel mechanisms of action and potential therapeutic benefits.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-Quinazolinecarboxylic acid, 1,2,3,4-tetrahydro-2-methyl-4-oxo-, serves as a valuable compound for further exploration and development. Researchers utilize its properties to design and synthesize new drug candidates with improved pharmacological profiles, targeting a wide range of diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 129768-69-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,7,6 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 129768-69:
(8*1)+(7*2)+(6*9)+(5*7)+(4*6)+(3*8)+(2*6)+(1*9)=180
180 % 10 = 0
So 129768-69-0 is a valid CAS Registry Number.
129768-69-0Relevant academic research and scientific papers
Synthesis of chrysogine, a metabolite of Penicillium chrysogenum and some related 2-substituted 4-(3H)-quinazolinones
Bergman, Jan,Brynolf, Anna
, p. 1295 - 1310 (2007/10/02)
Syntheses of both enantiomers of chrysogine, 2-(α-hydroxyethyl)-4(3H)-quinazolinone, 1 from 2-ammobenzamide are reported. Thus reaction of 2-aminobenzamide and optically active α-acetoxypropionyl chloride gave 9, which upon saponification and cyclization induced by aqueous sodium carbonate at room temperature gave chrysogine. The enantiomeric purity of 1 was determined by NMR. Inversion of (-)-(S)-1, using the Mitsunobo reaction, gave (+)-(R)-1. Reduction of 2-acetyl-4(3H)-qumazolinone 2 with baker's yeast gave the S-enantiomer of 1. The cyclization method used could be extended and a number of 2-(a-hydroxy)alkyl-4-(3H)-quinazolinones are also reported.
