129778-55-8

Basic information

• Product Name: (3S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-phenylsulfanyl-dihydro-furan-2-one
• CAS NO: 129778-55-8
• Molecular Weight: 462.685
• Mol File: 129778-55-8.mol

Chemical Properties

• CAS DataBase Reference: (3S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-phenylsulfanyl-dihydro-furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-phenylsulfanyl-dihydro-furan-2-one(129778-55-8)
• EPA Substance Registry System: (3S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-phenylsulfanyl-dihydro-furan-2-one(129778-55-8)

Safety Data

• Hazardous Substances Data: 129778-55-8(Hazardous Substances Data)

Upstream product

• 102717-29-3 (5S)-5-({[tert-butyl(diphenyl)silyl]oxy}methyl)dihydrofuran-2(3H)-one 
• 139524-52-0 6,6-Dimethyl-1-phenylsulfanyl-piperidin-2-one 
• 125440-13-3 (S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-trimethylsilanyloxy-2,3-dihydro-furan 
• 931-59-9 benzenesulfenyl chloride 
• 882-33-7 diphenyldisulfane 
• 36452-23-0 N-(phenylthio)-ε-caprolactam 

Relevant articles and documents

Diastereoselective Sulfenylation Reactions Employing N-(Phenylthio)lactams under Nonbasic Conditions

Silyl enol ethers and silyl ketene acetals react with sulfenamides in the presence of trimethylsilyl triflate to give the corresponding trans-sulfenylated ketones and lactones.

Stereoselectivity in the Coupling Reaction between 2-Phenylthio-2,3-dideoxyribose and Silylated Pyrimidine Bases

Coupling reaction between 2-α-phenylthio-2,3-dideoxyribose and silylated pyrimidine bases in the presence of SnCl4 proceeded stereoselectively to give the β-anomers.These nucleosides were converted to 2',3'-dideoxy-2',3'-didehydronucleosides by oxidation

A general method for controlling glycosylation stereochemistry in the synthesis of 2′-deoxyribose nucleosides

Glycosylation reactions of 2-arylsulfinyl-O-acetylribosides6 with silylated thymine11 produce 2′-deoxyribose nucleosides with high β-selectivity. An application of this directing effect in the synthesis of the antiretroviral agent D4T,2, is described. Glycosylation reactions of 2-arylsulfinyl-O-acetylribosideswith silylated thymine produce 2′-deoxyribose nucleosides with high β-selectivity. An application of this directing effect in the synthesis of the antiretroviral agent D4T is described. (Chemical Equation Presented).