129780-81-0

Basic information

• Product Name: 4-<<(4-aminopteridin-6-yl)methyl>methylamino>benzoic acid
• Synonyms: 4-<<(4-aminopteridin-6-yl)methyl>methylamino>benzoic acid
• CAS NO: 129780-81-0
• Molecular Weight: 310.315
• Mol File: 129780-81-0.mol

Chemical Properties

• CAS DataBase Reference: 4-<<(4-aminopteridin-6-yl)methyl>methylamino>benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-<<(4-aminopteridin-6-yl)methyl>methylamino>benzoic acid(129780-81-0)
• EPA Substance Registry System: 4-<<(4-aminopteridin-6-yl)methyl>methylamino>benzoic acid(129780-81-0)

Safety Data

• Hazardous Substances Data: 129780-81-0(Hazardous Substances Data)

Upstream product

• 40127-91-1 2-Amino-5-chloromethylpyrazine-3-carbonitrile 
• 10541-83-0 N-methyl-p-aminobenzoic acid 
• 3473-63-0 formamidine acetic acid 
• 43111-44-0 4-<<(2-amino-3-cyanopyrazin-5-yl)methyl>methylamino>benzoic acid 

Downstream Products

• 129780-82-1 di-tert-butyl N-<4-<<(4-aminopteridin-6-yl)methyl>methylamino>benzoyl>-L-glutamate 

Relevant articles and documents

Synthesis and biological activity of the 2-desamino and 2-desamino-2-methyl analogues of aminopterin and methotrexate

The previously undescribed 2-desamino and 2-desamino-2-methyl analogues of aminopterin (AMT) and methotrexate (MTX) were synthesized from 2-amino-5-(chloromethyl)pyrazine-3- carbonitrile. The AMT analogues were obtained via a three-step sequence consistin

Desamino-aminopterin and -methotrexate

A compound having the structure STR1 in which R1 is hydrogen or a lower alkyl group and R2 is hydrogen or methyl.