1297961-63-7Relevant academic research and scientific papers
Ruthenium-catalyzed synthesis of 5-amino-1,2,3-triazole-4-carboxylates for triazole-based scaffolds: Beyond the Dimroth rearrangement
Ferrini, Serena,Chandanshive, Jay Zumbar,Lena, Stefano,Comes Franchini, Mauro,Giannini, Giuseppe,Tafi, Andrea,Taddei, Maurizio
, p. 2562 - 2572 (2015)
The 5-amino-1,2,3-triazole-4-carboxylic acid is a suitable molecule for the preparation of collections of peptidomimetics or biologically active compounds based on the triazole scaffold. However, its chemistry may be influenced by the possibility of under
Microwave-assisted aminocarbonylation of ynamides by using catalytic [Fe3(CO)12] at low pressures of carbon monoxide
Pizzetti, Marianna,Russo, Adele,Petricci, Elena
supporting information; experimental part, p. 4523 - 4528 (2011/06/20)
The microwave-assisted aminocarbonylation of ynamides at low pressures of CO is reported. A new class of (E)-acrylamides that are potentially suitable for several applications has been regioselectively synthesized after microwave irradiation for only 20 min by using eco-friendly [Fe3(CO) 12] as the catalyst precursor and triethylamine as the ligand. This transformation is atom economic as all reactants are used in stoichiometric quantities. Furthermore, the transformation is efficiently applied to the alkoxycarbonylation of alkynes as well. Moreover, running these reactions under microwave irradiation allows the simplification of the reaction conditions with remarkable reductions in time, temperature and gas pressure.
