1298029-82-9

Upstream product

• 1298029-75-0 (7-bromo-3,4-dihydro-2H-pyrido[2,3-e]-[1,2,4]-thiadiazine 1,1-dioxid-4-yl)acetic acid methyl ester 
• 76283-09-5 4-bromo-2-fluorobenzyl bromide 
• 1298029-72-7 (7-bromo-4H-pyrido[2,3-e]-[1,2,4]-thiadiazine 1,1-dioxid-4-yl)acetic acid methyl ester 
• 868963-98-8 2-amino-5-bromopyridine-3-sulphonyl chloride 
• 1093953-89-9 7-bromo-4H-pyrido[2,3-e]-[1,2,4]-thiadiazine 1,1-dioxide 
• 869008-16-2 2-amino-5-bromo-3-pyridinesulfonamide 
• 1072-97-5 5-bromo-2-pyridylamine 

Downstream Products

• 1298029-97-6 [2-(4-bromo-2-fluorobenzyl)-7-bromo-3,4-dihydro-2H-pyrido[2,3-e]-[1,2,4]-thiadiazine 1,1-dioxid-4-yl] acetic acid 

Relevant academic research and scientific papers

Design and synthesis of potent and selective aldose reductase inhibitors based on pyridylthiadiazine scaffold

A series of pyrido[2,3-e]-[1,2,4]-thiadiazine 1,1-dioxide acetic acid derivatives were synthesized and tested for their inhibitory activity against aldose reductase (ALR2). These derivatives were found to be potent aldose reductase inhibitors with IC