1298029-86-3Relevant academic research and scientific papers
Pyridothiadiazine derivatives as aldose reductase inhibitors having antioxidant activity
Zhu, Shaojuan,Zhang, Shuzhen,Hao, Xin,Qin, Xiangyu,Parveen, Shagufta,Yang, Shaoqi,Ma, Bing,Zhu, Changjin
, p. 126 - 130 (2016/12/03)
A series of aldose reductase (ALR2) inhibitors based on pyridothiadiazine were prepared and evaluated for their activities in ALR2 inhibition, DPPH scavenging, and MDA inhibition. Comparison studies were carried out between analogs having either hydroxyl
Design and synthesis of potent and selective aldose reductase inhibitors based on pyridylthiadiazine scaffold
Chen, Xin,Yang, Yanchun,Ma, Bing,Zhang, Shuzhen,He, Minlan,Gui, Dequan,Hussain, Saghir,Jing, Chaojun,Zhu, Changjin,Yu, Qun,Liu, Yan
experimental part, p. 1536 - 1544 (2011/05/06)
A series of pyrido[2,3-e]-[1,2,4]-thiadiazine 1,1-dioxide acetic acid derivatives were synthesized and tested for their inhibitory activity against aldose reductase (ALR2). These derivatives were found to be potent aldose reductase inhibitors with IC
