1298087-11-2

Upstream product

• 1316735-67-7 C₂₆H₃₂O₂SSi 
• 1298087-06-5 (1R,2R,4R,6R)-1-methyl-2-((Z)-2-(dimethyl(phenyl)silyl)-2-(phenylsulfonyl)vinyl)-4-(prop-1-en-2-yl)-7-oxa-bicyclo[4.1.0]heptan-2-ol 
• 1298087-09-8 C₃₁H₄₂O₄SSi₂ 
• 62-23-7 4-nitro-benzoic acid 
• 1298087-05-4 (1R,2R,4R,6R)-1-methyl-2-(2-(phenylthio)ethynyl)-4-(prop-1-en-2-yl)-7-oxa-bicyclo[4.1.0] heptan-2-ol 
• 36616-60-1 (1R,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]heptan-2-one 
• 6485-40-1 (R)-Carvone 

Relevant academic research and scientific papers

Synthesis of bicyclo[4.2.0]octan-2-ol, a substructure of solanoeclepin A

A sesterterpenoid solanoeclepin A (1) has a unique structure including a bicyclo[4.2.0]octane substructure, for which a new synthetic methodology is explored particularly to cyclize functionalized cyclobutane rings. An optically active (R)-carvone and a racemic cyclohexenone were each converted into the respective epoxyvinylsulfones, and then subjected to the heteroatom-directed conjugate addition (HADCA) by a lithium acetylide nucleophile. The intermediate carbanions from HADCA were used for the following epoxide opening reaction yielding the four-membered carbocyclic products.