1298119-63-7Relevant academic research and scientific papers
Exercising regiocontrol in palladium-catalyzed asymmetric prenylations and geranylation: Unifying strategy toward flustramines A and B
Trost, Barry M.,Malhotra, Sushant,Chan, Walter H.
, p. 7328 - 7331 (2011)
Pd-catalyzed asymmetric prenylation of oxindoles to afford selectively either the prenyl or reverse-prenyl product has been demonstrated. Control of the regioselectivity in this transformation is governed by the choice of ligand, solvent, and halide additive. The resulting prenylated and reverse-prenylated products were transformed into ent-flustramides and ent-flustramines A and B. Additionally, control of the regio-and diastereoselectivity was obtained using π-geranylpalladium complexes.
