1298133-38-6

Basic information

• Product Name: (R)-SpiroPAP-tBu
• Synonyms: (R)-SpiroPAP-tBu;(R)-DTB-SpiroPAP-4-tBu;N-[(1R)-7'-[Bis[3,5-bis(tert-butyl)phenyl]phosphino]-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-inden]-7-yl]-4-tert-butyl-2-pyridinemethanamine,99%e.e.
• CAS NO: 1298133-38-6
• Molecular Formula: C₅₅H₇₁N₂P
• Molecular Weight: 791.139401
• Mol File: 1298133-38-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 86-88°C
• Appearance: white/solid
• Sensitive: air sensitive
• CAS DataBase Reference: (R)-SpiroPAP-tBu(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-SpiroPAP-tBu(1298133-38-6)
• EPA Substance Registry System: (R)-SpiroPAP-tBu(1298133-38-6)

Safety Data

• Hazardous Substances Data: 1298133-38-6(Hazardous Substances Data)

Usage

Reaction

Enantioselective synthesis of chiral 1,2-amino alcohols via asymmetric hydrogenation of α-amino ketones with chiral spiro iridium catalysts.

Upstream product

• 1219025-18-9 (R)-7′-bis-(3,5-di-tert-butylphenyl)phosphino-7′-amino-1,1′-spiroindene 

Relevant articles and documents

An additional coordination group leads to extremely efficient chiral iridium catalysts for asymmetric hydrogenation of ketones

What a turnover! An efficient chiral iridium catalyst that bears a tridentate spiro aminophosphine ligand catalyzes the asymmetric hydrogenation of ketones with excellent enantioselectivities (up to 99.9 % ee) and extremely high turnover numbers (TONs; as high as 4 550 000). Copyright