129819-17-6Relevant articles and documents
NICKEL-CATALYZED REACTIONS OF THIAZOLES, ISOXAZOLES, OXAZOLINES AND THIAZOLINES WITH GRIGNARD REAGENTS
Wenkert, Ernest,Han, Aili
, p. 929 - 937 (2007/10/02)
Grignard reagents convert thiazoles, isoxazoles, oxazolines and thiazolines into N-vinylimines, β-amino-α,β-unsaturated ketones, tetrahydrooxazoles and tetrahydrothiazoles, respectively, under the influence of phosphine-ligated nickel species.The reaction characteristics and the uncatalyzed reactions are described.