129840-81-9Relevant academic research and scientific papers
Synthesis and Stereoselective Reduction of (+/-)-, (+)- and (-)-6-Substituted-6-azabicyclooctan-3-one
Pitner, J. Bruce,Abraham, Philip,Joo, Young J.,Triggle, David J.,Carroll, F. Ivy
, p. 1375 - 1381 (2007/10/02)
Starting with 6-oxabicyclooct-3-en-7-one 6, a three step, general synthetic route to both racemic and optically active 6-substituted 6-azabicyclooctan-3-ones has been developed.Opening of the lactone ring of 6 with amines gave amides which w
A concise synthesis of (±)-, (+)-, and (-)-6-methyl-6-azabicyclo[3. 2.1]octan-3α-ol
Philip, Abraham,Pitner, J. Bruce,Joo, Young J.,Triggle, David J.,Carroll, F. Ivy
, p. 984 - 985 (2007/10/02)
(±)-6-Methyl-6-azabicyclo[3.2.1]octan-3-one (1c) was prepared in three steps from 6-oxabicyclo[3.2.1]oct-3-en-7-one, and stereoselective reduction of (1c) provided (±)-6-methyl-6-azabicyclo[3.2.1]octan- 3α-ol (1a); adaptation of the sequence provided the
