129871-69-8Relevant academic research and scientific papers
Reactions of Trialkylsilyl Trifluoromethanesulfonates, X. - N-(Trifluoroacetyl)-α,β-didehydro-α-amino Carboxylic Acid Esters from 2--3-(trimethylsiloxy)carboxylic Acid Esters by Elimination of Trimethylsilanol
Seethaler, Toni,Simchen, Gerhard
, p. 11 - 17 (2007/10/02)
α-Amino-β-(trimethylsiloxy)carboxylates 4 are obtained by trimethylsiloxy alkylation of the ketene acetal 1 with aldehydes 2 in the presence of trimethylsilyl triflate (3). β-Elimination of trimethylsilanol from the esters 4 by means of trifluoroacetic acid anhydride (8) or methanesulfonic acid anhydride (15) yields (Z)-didehydro amino acid esters 7.The course of the elimination reaction is studied.
