1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine, also known as PAF C-16 Carboxylic acid, is a naturally occurring phospholipid that plays a significant role in various biological processes. It is produced through two distinct pathways, "remodeling" and "de novo," and acts as a potent mediator of neutrophil migration, reactive oxygen species production, and IL-6. The carboxylic acid modification at the end of the C-16 alkyl chain provides a convenient site for chemical crosslinking, making it a versatile molecule for various applications.
129879-41-0
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Basic information
- Product Name: 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine
- Synonyms: 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine;PAF C-16 Carboxylic Acid;PKDXOBRCEXMRQQ-RUZDIDTESA-N
- CAS NO:129879-41-0
- Molecular Formula: C26H52NO9P
- Molecular Weight: 553.666141
- EINECS: N/A
- Product Categories: N/A
- Mol File: 129879-41-0.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: °Cat760mmHg
- Flash Point: °C
- Appearance: /
- Density: g/cm3
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine(CAS DataBase Reference)
- NIST Chemistry Reference: 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine(129879-41-0)
- EPA Substance Registry System: 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine(129879-41-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 129879-41-0(Hazardous Substances Data)
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129879-41-0 Usage
Uses
Used in Pharmaceutical Applications:1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine is used as a therapeutic agent for the treatment of various pathological processes, including necrotizing enterocolitis, inflammation, asthma, and allergy. Its ability to modulate immune responses and interact with cellular signaling pathways makes it a promising candidate for the development of new drugs targeting these conditions.
Used in Drug Delivery Systems:
In the pharmaceutical industry, 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine is used as a component in drug delivery systems. Its carboxylic acid group allows for the development of novel drug carriers, such as organic and metallic nanoparticles, which can enhance the delivery, bioavailability, and therapeutic outcomes of various drugs.
Used in Research Applications:
In the field of biomedical research, 1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine is used as a valuable tool for studying the roles of phospholipids in cellular processes and their involvement in various diseases. Its unique structure and functional groups enable researchers to investigate the molecular mechanisms underlying its biological activities and potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 129879-41-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,8,7 and 9 respectively; the second part has 2 digits, 4 and 1 respectively.Calculate Digit Verification of CAS Registry Number 129879-41:
(8*1)+(7*2)+(6*9)+(5*8)+(4*7)+(3*9)+(2*4)+(1*1)=180
180 % 10 = 0
So 129879-41-0 is a valid CAS Registry Number.
InChI:InChI=1/C26H52NO9P/c1-24(28)36-25(23-35-37(31,32)34-21-19-27(2,3)4)22-33-20-17-15-13-11-9-7-5-6-8-10-12-14-16-18-26(29)30/h25H,5-23H2,1-4H3,(H-,29,30,31,32)/t25-/m1/s1
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1-O-(15-carboxypentadecyl)-2-O-acetylglycero-3-phosphorylcholine
