129886-60-8

Basic information

• Product Name: (S)-2-[(2R,4S,5R)-4-Methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-propan-1-ol
• CAS NO: 129886-60-8
• Molecular Weight: 375.489
• Mol File: 129886-60-8.mol

Chemical Properties

• CAS DataBase Reference: (S)-2-[(2R,4S,5R)-4-Methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-[(2R,4S,5R)-4-Methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-propan-1-ol(129886-60-8)
• EPA Substance Registry System: (S)-2-[(2R,4S,5R)-4-Methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-propan-1-ol(129886-60-8)

Safety Data

• Hazardous Substances Data: 129886-60-8(Hazardous Substances Data)

Upstream product

• 212912-47-5 2RS,4S,5R-4-Methyl-3-p-methylphenylsulphonyl-2-methoxy-5-phenyl-1,3-oxazolidine 
• 58107-41-8 N-[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]-4-methylbenzenesulfonamide 
• 129886-58-4 (R)-2-[(2R,4S,5R)-4-Methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-thiopropionic acid S-tert-butyl ester 
• 102146-11-2 1-tert-butylthio-1-(tert-butyldimethylsilyloxy)prop-1-ene 

Downstream Products

• 129886-61-9 (2R,4S,5R)-2-((S)-2-Benzyloxy-1-methyl-ethyl)-4-methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidine 

Relevant articles and documents

NOREPHEDRINE DERIVED 2-METHOXY OXAZOLIDINES AS CHIRAL FORMYL CATION EQUIVALENTS

Lewis acid catalyzed reaction of silylenolethers with 1 followed by a straightforward nondestructive removal of the chiral auxiliary affords the corresponding aldehydes in good e.e.Compound 1 respresents the first effective synthetic equivalent of formyl cation.

STEREOCONVERGENT CROTYLSTANNANE ADDITION TO NOR-EPHEDRINE-DERIVED 2-METHOXY OXAZOLIDINES. A CLUE TOWARDS A SYNCLINAL TRANSITION STATE GEOMETRY

The Lewis acid promoted addition of crotyl-n-tributylstannane to a nor-ephedrine-derived 2-methoxy-oxazolidine has been studied.This stereoconvergent reaction allows highly selective C-C bond formation and takes place with opposite stereochemistry with respect to the analogous silylketenethioacetal addition.This result suggests a preference for a synclinal transition state geometry.