129951-45-7 Usage
Description
4-Chloro-5-fluoro-2-nitrobenzoic Acid is an organic compound characterized by the presence of a benzene ring with a chloro, fluoro, and nitro substituent at the 4th, 5th, and 2nd positions, respectively. It is a key intermediate in the synthesis of various pharmaceutical compounds due to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
4-Chloro-5-fluoro-2-nitrobenzoic Acid is used as an intermediate in the synthesis of Albaconazole (H761395), an antifungal agent with neuroprotective properties. Its unique structure allows for the development of new drugs with improved efficacy and safety profiles.
Used in Synthesis of Neuroprotective Agents:
4-Chloro-5-fluoro-2-nitrobenzoic Acid plays a crucial role in the development of neuroprotective agents, such as Albaconazole, which can help protect the nervous system from damage and degeneration. This makes it a valuable compound in the search for new treatments for neurological disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 129951-45-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,9,5 and 1 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 129951-45:
(8*1)+(7*2)+(6*9)+(5*9)+(4*5)+(3*1)+(2*4)+(1*5)=157
157 % 10 = 7
So 129951-45-7 is a valid CAS Registry Number.
129951-45-7Relevant articles and documents
Process for the preparation of fluorinated benzoic acids
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, (2008/06/13)
A process for the preparation of 2-chloro-4,5-difluorobenzoic acid and 2,4,5-trifluorobenzoic acid as well as synthetic intermediates useful in and prepared according thereto, comprising reacting a nitrobenzene having the formula STR1 wherein X is chloro or fluoro, with an appropriate carbanion to form a compound having the formula STR2 wherein one of Y and Z is chloro and the other is nitro, and R is a radical selected from the group consisting of --CCl3, --CH2 NO2, --CH(NO2)R1, --CH(CO2 R1)2, --CH(C(O)R2)2, --CH(CN)CO2 R1, --CH(CO2 R1)COR2 and --COR2 where R1 is alkyl or arylalkyl and R2 is alkyl, aryl or arylalkyl and, where appearing more than once in such a radical, R1 and R2 may be the same or different at each occurrence.