129952-69-8Relevant articles and documents
Monoamine re-uptake inhibiting 1-ethyl>piperazines as potential antidepressants
Wieringa, J.,Meerendonk, A. van den,Steenvoorden, J.,Heeres, G.,Bakel, F. van,et al.
, p. 143 - 150 (2007/10/02)
A series of 1-ethyl>-4-(3-phenylpropyl)piperazines 17-50 (Figure 1) were prepared and tested as inhibitors of biogenic amine re-uptake.In our search for antidepressants, the relationship between their in vitro and in vivo activity as dopamine-re-uptake inhibitors is described quantitatively by using Retention Index values determined by reversed-phase liquid chromatography.
