1300-73-8 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 1300-73-8 differently. You can refer to the following data:
1. Liquid. Slightly soluble inwater;
soluble in alcohol and ether. Combustible.
2. There are six xylidine isomers. Xylidine,
mixed isomers (principally made up of 2,4-, 2,5-, and
2,6-isomers) is a pale yellow to brown liquid with a weak,
aromatic amine odor.
Uses
Different sources of media describe the Uses of 1300-73-8 differently. You can refer to the following data:
1. Chiefly in the manufacture of dyes.
2. Chemical intermediate in the manufacture
of pesticides, dyes, antioxidants, pharmaceuticals,
synthetic resins, and fragrances.
Definition
A varying mixture of isomers (2,3-; 2,4-; 2,5-; 2,6-).
Hazard
Toxic by ingestion, inhalation, and skin
absorption. Liver damage. Methemoglobinemia.
Possible carcinogen.
Health Hazard
Xylidine causes liver damage in
experimental animals and is a mild methemoglobin
former; it caused tumors of the nasal
cavity in rats.
There are six isomeric forms of xylidenes
with the commercial product consisting primarily
of the 2,4- and 2,6-isomers.
Safety Profile
Confirmed carcinogen.
Poison by intravenous route. Moderately
toxic by ingestion. This material, which so
closely resembles aniline in the character of
its toxic effects, is actually twice as toxic as
aniline. It can cause injury to the blood and
the liver. It does not necessarily give any
alarm or warning, such as cyanosis,
headache, and duziness, whch characterize
aniline poisoning. Thus, it may be
considered a more insidious poison than aniline, and severe and possibly fatal
intoxication may come about through skin
absorption. Combustible when exposed to
heat or flame. Can react vigorously with
oxidizing materials. To fight fire, use foam,
CO2, dry chemical. When heated to
decomposition it emits toxic fumes of NOx.
See also ANILINE and other xylidme
entries.
Potential Exposure
Xylidines are used in dyestuff
manufacture; as intermediates in the manufacture of pesticides,
antioxidants, pharmaceuticals, and other organic com
pounds.
Carcinogenicity
The IARC has determined that there is
sufficient evidence for the carcinogenicity of
2,6-xylidine in experimental animals and inadequate
evidence in humans.5 Overall, 2,6-
xylidine is considered possibly carcinogenic to
humans.
In genotoxic assays, 2,6-xylidine induced
sister chromatid exchanges and chromosomal
aberrations in cultured mammalian cells but
did not induce micronuclei in the bone marrow
of mice treated in vivo; conflicting results have
been reported in the Salmonella typhimurium
assay.
Shipping
UN1711/Xylidines, solid or liquid, Hazard
Class: 6.1; Labels: 6.1-Poisonous materials.
Incompatibilities
Vapor may form explosive mixture with
air. Contact with hypo chlorite salts and bleaches form
explosive chloroamines. Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates,
chlorine, bromine, fluorine, etc.); contact may cause fires
or explosions. Keep away from alkaline materials, strong
bases, strong acids, oxoacids, and epoxides. A chemical
base: Will neutralize acids to form salts plus water with an
exothermic reaction. May be incompatible with isocyanates,
halogenated organics, peroxides, phenols (acidic),
epoxides, anhydrides, and acid halides. Flammable gaseous
hydrogen is generated by amines in combination with
strong reducing agents such as hydrides, nitrides, alkali
metals, and sulfides.
Waste Disposal
Incineration; oxides of
nitrogen are removed from the effluent gas by scrubber,
catalytic, or thermal device.
Check Digit Verification of cas no
The CAS Registry Mumber 1300-73-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,3,0 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1300-73:
(6*1)+(5*3)+(4*0)+(3*0)+(2*7)+(1*3)=38
38 % 10 = 8
So 1300-73-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N/c1-6-3-4-8(9)7(2)5-6/h3-5H,9H2,1-2H3
