130000-40-7

Usage

Uses

Used in Agricultural Industry:
Thifluzamide is used as a fungicide for controlling Rhizoctonia spp. diseases on crops such as rice, potatoes, maize, grass, and other crops. It helps in protecting these crops from fungal infections, thereby ensuring their healthy growth and productivity.

InChI:InChI=1/C13H6Br2F6N2O2S/c1-4-22-10(12(16,17)18)9(26-4)11(24)23-8-6(14)2-5(3-7(8)15)25-13(19,20)21/h2-3H,1H3,(H,23,24)

Upstream product

• 88149-49-9 2,6-dibromo-4-(trifluoromethoxy)aniline 
• 117724-63-7 2-methyl-4-trifluoromethylthiazole-5-carboxylic acid 
• 117724-64-8 2-methyl-4-trifluoromethylthiazole-5-carbonyl chloride 

Relevant academic research and scientific papers

Preparation method of thifluzamide

The invention belongs to the technical field of pesticide chemistry, and particularly relates to a preparation method of thifluzamide. The preparation method comprises the following steps: with 2-methyl-4-trifluoromethyl-5-thiazolecarboxylic acid as a raw material, performing an acylating chlorination reaction on the raw material and an acylating chlorination reagent in a solvent under the actionof a catalyst, then performing an amidation and condensation reaction on a product and 2,6-dibromo-4-trifluoromethoxyaniline under the catalytic action to obtain a final product thifluzamide. The thifluzamide product prepared by the preparation method provided by the invention has the yield range of 87-92% and the crude product content being higher than or equal to 96%; by the preparation method,the operation is simple, acyl chloride is not required to be purified, the preferred catalyst has an obvious effect and the overall reaction cycle is short.

Novel technology of preparing thifluzamide from thiazole acid

The invention provides a novel technology of preparing thifluzamide from thiazole acid. The invention relates to a preparation method of a bactericide namely thifluzamide, and belongs to the technicalfield of chemistry. The invention discloses a one-step synthesis method of thifluzamide, and the synthesis method is simple and high efficient. According to the synthesis method, 2-methyl-4-trifluoromethyl-1,3-thiazole formic acid and 2,6-dibromo-trifluoromethoxyl aniline are taken as the primary raw materials, and the bactericide namely thifluzamide is synthesized in one step without any intermediate treatment in the presence of a catalyst. The novel technology has the advantages that the step is simple, there are few post treatment steps, and the reaction period is shortened.

Pyrazolyl benzyl ether derivatives containing a fluoromethoxyimino group and use thereof as pesticides

The invention relates to novel pyrazolyl benzyl ethers, to a plurality of processes for their preparation and to their use for controlling harmful organisms.

Thifluzamide with improved efficacy

PCT No. PCT/JP97/00613 Sec. 371 Date Nov. 24, 1998 Sec. 102(e) Date Nov. 24, 1998 PCT Filed Feb. 28, 1997 PCT Pub. No. WO97/31908 PCT Pub. Date Sep. 4, 1997The present invention provides thifluzamide which has changed its crystalline form, its preparation method, and a pesticide composition containing thifluzamide as its effective ingredient. The rate of dissolution of the thifluzamide obtained is high and the pesticide compounds containing it has improved efficacy.

Thifluzamide with stabilized efficacy

The disclosed invention is thifluzamide with an altered crystalline form, prepared by heat-melting and then cooling, and agricultural chemical compositions comprising such a thifluzamide as its effective ingredient.

Thifluzamide polymorph with improved efficacy

The disclosed invention is thifluzamide with an altered crystalline form, prepared by heat-melting and then cooling, and agricultural chemical compositions comprising such a thifluzamide as its effective ingredient.