1300020-33-0

Basic information

• Product Name: (3R,4S)-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-4-(4-nitrophenyl)butan-2-one
• CAS NO: 1300020-33-0
• Molecular Weight: 463.605
• Mol File: 1300020-33-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4S)-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-4-(4-nitrophenyl)butan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4S)-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-4-(4-nitrophenyl)butan-2-one(1300020-33-0)
• EPA Substance Registry System: (3R,4S)-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-4-(4-nitrophenyl)butan-2-one(1300020-33-0)

Safety Data

• Hazardous Substances Data: 1300020-33-0(Hazardous Substances Data)

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 118171-02-1 1-(tert-butyldiphenylsilyloxy)-2-propanone 

Relevant articles and documents

Asymmetric syn-selective direct aldol reaction of protected hydroxyacetone catalyzed by primary amino acid derived bifunctional organocatalyst in the presence of water

A new series of water compatible primary-tertiary diamine catalysts derived from natural primary amino acids bearing a hydrophobic side chain have been synthesized. These new primary-tertiary diamine-Bronsted acid conjugates bifunctional organocatalysts efficiently catalyzes the asymmetric direct syn selective cross-aldol reaction of different protected hydroxyacetone with various aldehydes in high yield (94%) and high enantioselectivity (up to 97% ee of syn) and dr of 91:9 (syn/anti) under mild reaction conditions.