130010-35-4

Upstream product

• 89461-64-3 7Z,9E,11E,14Z-LTE₄ methyl ester 
• 72297-14-4 4-[(2S,3R)-((1Z,3E,5E,8Z)-3-Tetradeca-1,3,5,8-tetraenyl)-oxiranyl]-butyric acid methyl ester 
• 73958-00-6 4-[(2S,3R)-3-((1Z,3E)-5-Oxo-penta-1,3-dienyl)-oxiranyl]-butyric acid methyl ester 
• 73958-09-5 Phosphorane of (Z)-3-nonen-1-yl-triphenylphosponium bromide 
• 72345-92-7 rac-trans-(1E,3E,5Z,8Z)-(1,3,5,8-tetradecatetraenyl)oxiranebutanoic acid methyl ester 
• 78377-38-5 (E)-6-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hex-5-enoic acid methyl ester 
• 78377-38-5 (E)-6-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hex-5-enoic acid methyl ester 
• 82430-34-0 7,8-O-isopropylidene-7(R),8-dihydroxyoct-5-enoic acid 
• 78377-37-4 7,8-O-isopropylidene-7(R),8-dihydroxyoct-5-enoic acid 
• 102906-18-3 (E)-6-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hex-5-enoic acid 
• 102906-05-8 (Z)-6-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hex-5-enoic acid 
• 73427-12-0 methyl 6-formyl-5,6-trans-epoxyhexanoate 
• 17814-85-6 (4-carboxybutyl)triphenylphosphonium bromide 
• 75415-34-8 (7E,9E,11Z,14Z)-(5S,6R)-5-Hydroxy-6-[2-methoxycarbonyl-2-(2,2,2-trifluoro-acetylamino)-ethylsulfanyl]-icosa-7,9,11,14-tetraenoic acid methyl ester 

Relevant academic research and scientific papers

SYNTHESIS OF LEUKOTRIENES - NEW SYNTHESIS OF NATURAL LEUKOTRIENE A4

The acetonides of D- or L-glyceraldehyde are chiral synthons for an efficient and versatile synthesis of the natural leukotrienes A4, C4, D4 and E4 and equally can be used to prepare the corresponding unnatural analogues.