130014-74-3

Upstream product

• 130014-83-4 C₃₈H₆₆O₆Si₂ 
• 130014-84-5 (2R,4S,5R)-4-Benzyloxy-2-(2-benzyloxy-ethyl)-5-methoxy-5-methyl-8-(2-trimethylsilanyl-ethoxymethoxy)-octan-1-ol 
• 130014-72-1 (2R,4S,5R)-4-Benzyloxy-2-(2-benzyloxy-ethyl)-5-methoxy-5-methyl-8-(2-trimethylsilanyl-ethoxymethoxy)-octanal 
• 130014-81-2 (2S,4S)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-2-[(R)-1-methoxy-1-methyl-4-(2-trimethylsilanyl-ethoxymethoxy)-butyl]-cyclopentanone 
• 130014-80-1 (1R,2R,4S)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-2-[(R)-1-methoxy-1-methyl-4-(2-trimethylsilanyl-ethoxymethoxy)-butyl]-cyclopentanol 
• 130033-83-9 (3R,5S,6R)-3-(tert-Butyl-dimethyl-silanyloxymethyl)-6-methoxy-6-methyl-9-(2-trimethylsilanyl-ethoxymethoxy)-nonane-1,5-diol 
• 130014-77-6 (1R,4S,5S,6S)-6-Benzyloxy-4-(3-hydroxy-propyl)-4-methyl-3-oxa-bicyclo[3.2.1]octan-2-one 
• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 
• 130014-73-2 (3R,5S,6R)-5-Benzyloxy-3-(2-benzyloxy-ethyl)-6-methoxy-6-methyl-2-[(E)-2-methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-pent-2-enyl]-9-(2-trimethylsilanyl-ethoxymethoxy)-2-trimethylsilanyloxy-nonanenitrile 
• 130014-78-7 (R)-2-((1R,2R,4S)-2-Benzyloxy-4-hydroxymethyl-cyclopentyl)-5-(2-trimethylsilanyl-ethoxymethoxy)-pentan-2-ol 
• 130014-70-9 {(1R,2R,4S)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-2-[(R)-1-methoxy-1-methyl-4-(2-trimethylsilanyl-ethoxymethoxy)-butyl]-cyclopentyloxymethyl}-benzene 
• 130014-79-8 (R)-2-[(1R,2R,4S)-2-Benzyloxy-4-(tert-butyl-dimethyl-silanyloxymethyl)-cyclopentyl]-5-(2-trimethylsilanyl-ethoxymethoxy)-pentan-2-ol 
• 130014-69-6 (1R,4S,5S,6S)-6-Benzyloxy-4-methyl-4-[3-(2-trimethylsilanyl-ethoxymethoxy)-propyl]-3-oxa-bicyclo[3.2.1]octan-2-one 
• 130014-71-0 (4S,6S)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-6-[(R)-1-methoxy-1-methyl-4-(2-trimethylsilanyl-ethoxymethoxy)-butyl]-tetrahydro-pyran-2-one 

Downstream Products

• 130014-85-6 (E)-(6R,7S,9R,10S)-9-Benzyloxy-7-(2-benzyloxy-ethyl)-10-methoxy-4,10-dimethyl-1-(2-methyl-[1,3]dioxolan-2-yl)-13-(2-trimethylsilanyl-ethoxymethoxy)-tridec-3-en-6-ol 
• 130014-85-6 (E)-(6S,7S,9R,10S)-9-Benzyloxy-7-(2-benzyloxy-ethyl)-10-methoxy-4,10-dimethyl-1-(2-methyl-[1,3]dioxolan-2-yl)-13-(2-trimethylsilanyl-ethoxymethoxy)-tridec-3-en-6-ol 
• 130014-86-7 2,2-Dimethyl-propionic acid (1R,2S,4R,5S)-4-benzyloxy-2-(2-benzyloxy-ethyl)-5-methoxy-5-methyl-1-[(E)-2-methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-pent-2-enyl]-8-(2-trimethylsilanyl-ethoxymethoxy)-octyl ester 
• 130014-86-7 2,2-Dimethyl-propionic acid (1S,2S,4R,5S)-4-benzyloxy-2-(2-benzyloxy-ethyl)-5-methoxy-5-methyl-1-[(E)-2-methyl-5-(2-methyl-[1,3]dioxolan-2-yl)-pent-2-enyl]-8-(2-trimethylsilanyl-ethoxymethoxy)-octyl ester 
• 130014-75-4 2,2-Dimethyl-propionic acid (3E,7Z)-(1S,11R,12S,14R)-12-benzyloxy-14-(2-benzyloxy-ethyl)-11-methoxy-3,7,11-trimethyl-cyclotetradeca-3,7-dienyl ester 
• 130014-75-4 2,2-Dimethyl-propionic acid (3E,7E)-(1S,11R,12S,14R)-12-benzyloxy-14-(2-benzyloxy-ethyl)-11-methoxy-3,7,11-trimethyl-cyclotetradeca-3,7-dienyl ester 
• 130014-87-8 2,2-Dimethyl-propionic acid (E)-(R)-1-[(1S,3R,4S)-3-benzyloxy-1-(2-benzyloxy-ethyl)-4-methoxy-4-methyl-7-oxo-heptyl]-3-methyl-7-oxo-oct-3-enyl ester 
• 130014-87-8 2,2-Dimethyl-propionic acid (E)-(S)-1-[(1S,3R,4S)-3-benzyloxy-1-(2-benzyloxy-ethyl)-4-methoxy-4-methyl-7-oxo-heptyl]-3-methyl-7-oxo-oct-3-enyl ester 

Relevant academic research and scientific papers

Total synthesis of (±)-crassin acetate methyl ether

The total synthesis of (±)-crassin acetate methyl ether consists of two major operations, macrocyclization and lactone ring formation. The basic stereochemical control unit was 5β-benzyloxynorbornan-2-one.