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130016-65-8

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130016-65-8 Usage

General Description

2-(2,5-DIMETHYL-PYRROL-1-YL)-PROPIONIC ACID is a chemical compound with the molecular formula C11H15NO2. It is a derivative of pyrrolidine and is commonly used as a non-steroidal anti-inflammatory drug (NSAID). It works by inhibiting the production of certain chemicals in the body that cause inflammation and pain. It is often prescribed to treat conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. 2-(2,5-DIMETHYL-PYRROL-1-YL)-PROPIONIC ACID is a white, crystalline powder that is soluble in organic solvents and has a molecular weight of 193.24 g/mol. It is an important pharmaceutical ingredient with therapeutic applications in managing pain and inflammation.

Check Digit Verification of cas no

The CAS Registry Mumber 130016-65-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,0,1 and 6 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 130016-65:
(8*1)+(7*3)+(6*0)+(5*0)+(4*1)+(3*6)+(2*6)+(1*5)=68
68 % 10 = 8
So 130016-65-8 is a valid CAS Registry Number.

130016-65-8Relevant articles and documents

Peptide Synthesis Using the Pyrrole Ring as an Amino Protecting Group

Kashima, Choji,Maruyama, Tatsuya,Harada, Kazuo,Hibi, Shigeki,Omote, Yoshimori

, p. 601 - 645 (2007/10/02)

The utility of a pyrrole ring as an amino protecting group for amino acids in peptide synthesis has been studied.The N-termini of various amino acids (1) were protected with a pyrrole ring by treatment with 2,5-dimethoxytetrahydrofuran (10) to give 2-substituted 2-(1-pyrrolyl)acetic acids (11).The peptide bond between (11) and amino acid methyl ester (2) was formed using N,N'-dicyclohexylcarbodiimide, and the pyrrole ring was cleaved by ozonolysis and hydrolysis without the cleavage of a peptide bond to give the corresponding dipeptide compounds (26) in good yields.

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