130048-18-9

Upstream product

• 94853-56-2 3-methyl-3-(4-methylphenyl)-pent-4-enal 
• 57318-21-5 (methoxymethyl)triphenylphosphonium chloride 
• 313990-14-6 1-methyl-4-(3-methylhexa-1,5-dien-3-yl)benzene 
• 66334-30-3 2(p-tolyl) 1-methoxy 1-propene 
• 122-00-9 para-methylacetophenone 
• 62083-22-1 2-methyl-2-(4-methylphenyl)-pent-4-en-1-al 
• 313990-15-7 4-methyl-4-p-tolyl-hex-5-en-1-ol 

Downstream Products

• 4608-44-0 2,3-dimethyl-3-(p-tolyl)cyclopentan-1-one 
• 313990-16-8 1-(5,5-dibromo-1-methyl-1-vinyl-pent-4-enyl)-4-methyl-benzene 
• 313990-18-0 1-methyl-4-(1-methyl-1-vinyl-pent-4-ynyl)-benzene 
• 380379-43-1 laurene 

Relevant academic research and scientific papers

A short synthesis of (±)-laurene: Mechanistic reinvestigation in palladium-catalyzed cycloreductions of 1,6-enynes

Two palladium-catalyzed cycloreduction strategies have been applied for the synthesis of laurene. Palladium-catalyzed cyclizations of 1,6-enynes initially form the corresponding alkylpalladium intermediates. While triethylsilane could directly reduce the intermediates to lead to the corresponding cycloreduced products, the intermediates in the presence of even excess formic acid underwent β-elimination to yield the dienes that were further reduced at the less hindered olefins to yield the cycloreduced products. (C) 2000 Elsevier Science Ltd.

A radical cyclisation based strategy to cuparenoids; synthesis of (+)-α-cuparenone, (+)-epilaurene and laurenes

Mercuric acetate catalysed one pot Claisen rearrangement of the cinnamyl alcohol 5, generated the pent-4-enal 9, which on homologation resulted the hex-5-enal 10. Radical cyclisation of the radical anion derived from 10, followed by oxidation provided the