1300720-55-1Relevant academic research and scientific papers
A strategy for neuraminidase inhibitors using mechanism-based labeling information
Hinou, Hiroshi,Miyoshi, Risho,Takasu, Yasuaki,Kai, Hirokazu,Kurogochi, Masaki,Arioka, Shingo,Gao, Xiao-Dong,Miura, Nobuaki,Fujitani, Naoki,Omoto, Shinya,Yoshinaga, Tomokazu,Fujiwara, Tamio,Noshi, Takeshi,Togame, Hiroko,Takemoto, Hiroshi,Nishimura, Shin-Ichiro
, p. 1048 - 1056 (2011)
A potent inhibitor for Vibrio cholerae neuraminidase (VCNA) was developed by using a novel two-step strategy, a target amino acid validation using mechanism-based labeling information, and a potent inhibitor search using a focused library. The labeling in
