1300740-55-9Relevant academic research and scientific papers
Solvent influence in the Rh-catalyzed intramolecular 1,6 C-H insertions: A general approach to the chromane and flavanone skeletons
Rosales, Antonio,Rodríguez-García, Ignacio,López-Sánchez, Cristóbal,álvarez-Corral, Míriam,Mu?oz-Dorado, Manuel
, p. 3071 - 3075 (2011)
Solvent polarity and nature of the ligands on the catalyst are crucial factors that control the regioselectivity of the Rh(II) promoted intramolecular 1,6 C-H insertions versus the β-elimination. We have explored the best conditions for the preparation of flavanones and chromenes through this approach. The procedure is also an excellent way of preparing stereochemically pure Z aryl-alkenes.
