1300745-71-4Relevant academic research and scientific papers
Synthesis of the phenanthrene and cyclohepta[ a ]naphthalene skeletons via gold(I)-catalyzed intramolecular cyclization of unactivated cyclic 5-(2-arylethyl)-1,3-dienes
Yeh, Ming-Chang P.,Lin, Ming-Nan,Chou, Yi-Shiang,Lin, Tern-Chi,Tseng, Li-Yu
body text, p. 4027 - 4033 (2011/07/06)
The gold(I)-catalyzed hydroarylation of cyclohexa-1,3-dienes bearing an aryl group and a gem-diester in the tether proceeds in a 1,4-addition manner and in a diastereoselective fashion to afford perhydrophenanthrene rings. The reaction proceeded via attack of the aryl group onto the gold-activated cyclic dienes followed by rearomatization and protodeauration to generate perhydrophenanthrenes in good yields. This hydroarylation can be applied to the synthesis of perhydrocyclohepta[a]naphthalenes from aryl-tethered cycloheptadienes and the gold(I) catalyst.
