1300747-70-9Relevant academic research and scientific papers
Evaluation of thiazole containing biaryl analogs as diacylglycerol acyltransferase 1 (DGAT1) inhibitors
Kadam, Kishorkumar S.,Jadhav, Ravindra D.,Kandre, Shivaji,Guha, Tandra,Reddy, M. Mahesh Kumar,Brahma, Manoja K.,Deshmukh, Nitin J.,Dixit, Amol,Doshi, Lalit,Srinivasan, Shaila,Devle, Jayendra,Damre, Anagha,Nemmani, Kumar V. S.,Gupte, Amol,Sharma, Rajiv
, p. 337 - 347 (2013/10/01)
Biphenyl carboxylic acids, exemplified by compound 5, are known potent inhibitors of diacylglycerol acyltransferase, DGAT1, an enzyme involved in the final committed step of triglyceride biosynthesis. We have synthesized and evaluated 2-phenylthiazole, 4-
