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2-broMo-3-iodopyridin-4-aMine
Cas No: 1300750-77-9
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ZHEJIANG JIUZHOU CHEM CO.,LTD
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2-Bromo-3-iodopyridin-4-amine
Cas No: 1300750-77-9
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coolpharm Ltd
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4-aminobenzo[c][1,2]oxaborol-1(3H)-ol
Cas No: 1300750-77-9
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Debye Scientific
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1300750-77-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1300750-77-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,0,0,7,5 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1300750-77:
(9*1)+(8*3)+(7*0)+(6*0)+(5*7)+(4*5)+(3*0)+(2*7)+(1*7)=109
109 % 10 = 9
So 1300750-77-9 is a valid CAS Registry Number.

1300750-77-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name	2-Bromo-3-Iodopyridin-4-Amine

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1300750-77-9 SDS

1300750-77-9Upstream product

7598-35-8 2-bromo-4-aminopyridine

1300750-77-9Downstream Products

1300750-87-1 4-bromo-2,3-diphenyl-1H-pyrrolo[3,2-c]pyridine

1300750-77-9Relevant articles and documents

Structure-based design of orally bioavailable 1 h -Pyrrolo[3,2- C ]pyridine inhibitors of mitotic kinase monopolar spindle 1 (MPS1)

Naud, Sébastien,Westwood, Isaac M.,Faisal, Amir,Sheldrake, Peter,Bavetsias, Vassilios,Atrash, Butrus,Cheung, Kwai-Ming J.,Liu, Manjuan,Hayes, Angela,Schmitt, Jessica,Wood, Amy,Choi, Vanessa,Boxall, Kathy,Mak, Grace,Gurden, Mark,Valenti, Melanie,De Haven Brandon, Alexis,Henley, Alan,Baker, Ross,McAndrew, Craig,Matijssen, Berry,Burke, Rosemary,Hoelder, Swen,Eccles, Suzanne A.,Raynaud, Florence I.,Linardopoulos, Spiros,Van Montfort, Rob L. M.,Blagg, Julian

, p. 10045 - 10065 (2014/01/17)

The protein kinase MPS1 is a crucial component of the spindle assembly checkpoint signal and is aberrantly overexpressed in many human cancers. MPS1 is one of the top 25 genes overexpressed in tumors with chromosomal instability and aneuploidy. PTEN-defic

PYRROLOPYRIDINEAMINO DERIVATIVES AS MPS1 INHIBITORS

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Page/Page column 65-66, (2012/10/07)

The present invention relates to the use of certain pyrrolopyridineamino derivatives (hereinafter referred to as "PPA derivatives"), particularly 1H-pyrrolo[3,2-c]pyridine-6- amino derivatives, to inhibit the spindle checkpoint function of Monospindle 1 (Mps1 – also known as TTK) kinases either directly or indirectly via interaction with the Mps kinase itself. In particular, the present invention relates to PPA derivatives for use as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of the PPA derivatives, and pharmaceutical compositions comprising them. Formula (I)

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1300750-77-9