130082-81-4Relevant articles and documents
Formation of trans Ring-Fused Compounds by an Alkylation-Radical Cyclization Sequence
Clive, Derrick L. J.,Manning, Hartford W.,Boivin, Taryn L. B.,Postema, Maarten H. D.
, p. 6857 - 6873 (2007/10/02)
Enolates derived from bicyclic lactones of type 1 (Scheme I) can be alkylated with 2-propynylic halides to give products 2, in which the unsaturated alkyl group is syn to the adjacent ring-fusion hydrogen.Reaction of 2 with sodium phenyl selenide and then
Construction of trans-Ring-fused Compounds by Radical Cyclization
Clive, Derrick L. J.,Manning, Hartford W.,Boivin, Taryn L. B.
, p. 972 - 974 (2007/10/02)
Enolates derived from bicyclic lactones of type (4) are alkylated with prop-2-ynylic (and allylic) bromides to give products (5) in which the unsaturated alkyl group is syn to the remaining ring-fusion hydrogen; prop-2-ynylic aldehydes can be used instead
